Keto Mac and Cheese Skillet Casserole

This Keto Mac and Cheese Skillet Casserole is a game changer. We love to eat it for dinner and also serve it on Sundays during football season. Mac and Cheese Skillet Casserole will definitely be part of the spread at our Super Bowl Party.

The Perfect One Pot Meal

This easy grain-free casserole recipe makes a wonderful dinner but is also good for so many other occasions. It’s the perfect one-pot potluck meal, given that it’s chock full of protein and vegetables, easy to make, and delicious.

Healthy Dinner Recipe for Kids

Keto Mac and Cheese Skillet Casserole has a bit of a kick to it! If you are making this healthy dinner recipe for children, you may want to reduce the smoked paprika.

Keto Mac and Cheese Skillet Casserole

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Servings 10



  • In a 10 inch cast iron skillet, cook beef until brown
  • Remove from heat and set aside
  • In a large bowl, Whisk heavy cream and eggs until smooth
  • Mix in smoked paprika, salt, and pepper
  • Stir in spaghetti squash, parmesan, and 1 cup cheddar
  • Stir in ground beef
  • Transfer mixture back to cast iron skillet
  • Top with remaining cup of cheddar
  • Bake at 350°F until bubbling around the edges 40-50 minutes
  • Cool 15 minutes
  • Serve
Prep Time 20 mins
Cook Time 50 mins
Total Time 1 hr 10 mins
Tried this recipe?Mention @elanaspantry or tag #elanaspantry!

Quick and Easy Keto Dinner Recipe

To make this keto casserole recipe even easier, I cook the spaghetti squash the night before. That way I simply brown the meat, toss the ingredients in a bowl, and throw it in the oven for a wonderful grain-free dinner.

How to Cook Spaghetti Squash

If you haven’t cooked spaghetti squash before take a look at my How to Cook Spaghetti Squash guide. In it, I show you the easiest way ever to cook this low-carb winter squash.

More Low-Carb Keto Dinner Recipes

Here are some of my other easy low-carb keto dinner recipes!

This post is an oldie but goodie from the archives. I first shared this recipe in January 2017.

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paleo cooking from elana's pantryGluten-Free Almond Flour Cookbook

I can only say that this recipe is AMAZING!! I made it last night and didn’t change a thing –incredibly delicious and satisfying!! Thank you for all you do!!


112 responses to “Keto Mac and Cheese Skillet Casserole”

  1. This is DELICIOUS. Added Garlic(TBLS) and dry mustard (maybe a tsp?) And we topped with broccoli. The Broccoli crisps up for a really nice texture. We were craving tater tot hotdish, and this was a fantastic Keto substitute.

  2. I’ve made this recipe 3 times now in the last 6 weeks It’s amazing and versatile. I always start with the base recipe, but I’ve used both ground beef and ground pork (with COVID-19, my meat selection is a bit spotty) and added onion/garlic/peppers, etc. No matter if I’m sticking with the recipe as is, or using different meat or adding veggies, it’s a hit in my house! Thank you for the recipe. It is amazing.

  3. This is one of your best recipes! My whole family loves it. I think I could take this to a party, and the the pickiest eaters would devour it. Thank you once again for a yummy and healthy easy recipe.

    • Christine, sorry for the tardy reply! The boys just went back to college and I’m catching up on my life. I’m so happy to hear you are enjoying this recipe and that your whole family loves it. Let me know if you take it to a party :-)

  4. I have frozen half and reheated it and it was delicious. I have also added sautéed mushrooms cook until all the water is absorbed and eliminated the beef and loved it!

  5. Hi Elana, I am making this tonight, can I bake then portion out half the recipe into freezer containers? When unthawed will it heat up in the microwave ok?

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Recipes » Dinners » Keto Mac and Cheese Skillet Casserole